› 5vyl

X-ray diffraction
3.51Å resolution

Crystal Structure of N-terminal half of Herpes Simplex virus Type 1 UL37 protein

Released:
DOI: 10.2210/pdb5vyl/pdb
PDB entry 5vyl coloured by chain, front view.
PDB entry 5vyl coloured by chain, side view.
PDB entry 5vyl coloured by chain, top view.
Source organism: Human alphaherpesvirus 1 strain 17
Primary publication:
Crystal Structure of the N-Terminal Half of the Traffic Controller UL37 from Herpes Simplex Virus 1.
Koenigsberg AL, Heldwein EE
J Virol 91 (2017)
PMID: 28768862

Function and Biology Details

Reaction catalysed: 
Protein L-glutamine + H(2)O = protein L-glutamate + NH(3)
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145211 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inner tegument protein Chain: A
Molecule details ›
Chain: A
Length: 579 amino acids
Theoretical weight: 61.8 KDa
Source organism: Human alphaherpesvirus 1 strain 17
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P10221 (Residues: 1-575; Coverage: 51%)
Gene name: UL37
Sequence domains: Herpesvirus UL37 tegument protein

Ligands and Environments

1 bound ligand:
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P6122
Unit cell:
a: 138.232Å b: 138.232Å c: 164.22Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.244 0.24 0.282
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

HSV-1 Cytoplasmic Envelopment and Egress.
Ahmad et al. (2020)
3 more

3 mentions without citation

Crystal Structure of the N-Terminal Half of the Traffic Controller UL37 from Herpes Simplex Virus 1.
Koenigsberg et al. (2017)
2 more