› 5vyh

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125661 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spike protein S1 Chain: A
Molecule details ›
Chain: A
Length: 343 amino acids
Theoretical weight: 38.51 KDa
Source organism: Middle East respiratory syndrome-related coronavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: K9N5Q8 (Residues: 18-353; Coverage: 25%)
Gene names: 3, S
Sequence domains: Betacoronavirus-like spike glycoprotein S1, N-terminal

Ligands and Environments

4 bound ligands:
Ligand NAG 8 x NAG
Ligand FOL 1 x FOL
Ligand MPD 1 x MPD
Ligand IMD 1 x IMD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL14-1
Spacegroup: P212121
Unit cell:
a: 49.8Å b: 84.37Å c: 108Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.19 0.222
Expression system: Homo sapiens

Quick links

Citations

175 review citations

SARS-CoV-2 vaccines in development.
Krammer F. (2020)
174 more

4 mentions without citation

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Pallesen et al. (2017)
3 more