PDBe 5vx0

X-ray diffraction
1.6Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Bcl-2 homologous antagonist/killer Chains: A, C
Molecule details ›
Chains: A, C
Length: 170 amino acids
Theoretical weight: 19.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16611 (Residues: 23-186; Coverage: 78%)
  • Best match: Q16611-2 (Residues: 23-116)
Gene names: BAK, BAK1, BCL2L7, CDN1
Sequence domains: Apoptosis regulator proteins, Bcl-2 family
Bcl-2-like protein 11 Chains: B, D
Molecule details ›
Chains: B, D
Length: 26 amino acids
Theoretical weight: 3.26 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: O43521 (Residues: 141-166; Coverage: 13%)
Gene names: BCL2L11, BIM

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P212121
Unit cell:
a: 48.092Å b: 63.231Å c: 121.038Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.165 0.2
Expression systems:
  • Escherichia coli
  • Not provided