X-ray diffraction
2Å resolution

Human UDP-Glucose Dehydrogenase with UDP-Xylose Bound to the Co-enzyme Site


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
UDP-glucose 6-dehydrogenase Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 495 amino acids
Theoretical weight: 55.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: O60701 (Residues: 1-494; Coverage: 100%)
Gene name: UGDH
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 89.08Å b: 196.49Å c: 111.26Å
α: 90° β: 111.91° γ: 90°
R R work R free
0.158 0.156 0.19
Expression system: Escherichia coli