GO terms
Biochemical function:
- protein-containing complex binding
- protein serine/threonine kinase activator activity
- identical protein binding
- deubiquitinase activator activity
- type III transforming growth factor beta receptor binding
- type I transforming growth factor beta receptor binding
- enzyme binding
- growth factor activity
- protein binding
- transforming growth factor beta receptor binding
- cytokine activity
- type II transforming growth factor beta receptor binding
- antigen binding
Biological process:
- positive regulation of cardiac muscle cell differentiation
- positive regulation of stem cell proliferation
- positive regulation of primary miRNA processing
- positive regulation of endothelial cell apoptotic process
- positive regulation of chemokine (C-X-C motif) ligand 2 production
- embryonic liver development
- cellular response to insulin-like growth factor stimulus
- regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
- positive regulation of receptor signaling pathway via STAT
- positive regulation of vasculature development
- negative regulation of protein localization to plasma membrane
- positive regulation of miRNA transcription
- negative regulation of miRNA transcription
- regulation of miRNA transcription
- positive regulation of mesenchymal stem cell proliferation
- response to salt
- positive regulation of extracellular matrix assembly
- positive regulation of protein localization to nucleus
- negative regulation of hyaluronan biosynthetic process
- cellular response to virus
- liver regeneration
- extrinsic apoptotic signaling pathway
- positive regulation of canonical Wnt signaling pathway
- positive regulation of branching involved in ureteric bud morphogenesis
- extracellular matrix assembly
- stem cell proliferation
- odontoblast differentiation
- positive regulation of mononuclear cell migration
- cellular response to transforming growth factor beta stimulus
- cellular response to dexamethasone stimulus
- cellular response to ionizing radiation
- cellular response to hypoxia
- cellular response to low-density lipoprotein particle stimulus
- cellular response to growth factor stimulus
- cellular response to glucose stimulus
- cellular response to mechanical stimulus
- response to cholesterol
- positive regulation of ERK1 and ERK2 cascade
- lens fiber cell differentiation
- regulation of enamel mineralization
- negative regulation of biomineral tissue development
- Langerhans cell differentiation
- connective tissue development
- retina vasculature development in camera-type eye
- regulation of cartilage development
- regulation of branching involved in mammary gland duct morphogenesis
- branch elongation involved in mammary gland duct branching
- mammary gland branching involved in thelarche
- bronchiole development
- positive regulation of SMAD protein signal transduction
- frontal suture morphogenesis
- face morphogenesis
- regulation of blood vessel remodeling
- canonical Wnt signaling pathway
- phospholipid homeostasis
- ventricular cardiac muscle tissue morphogenesis
- positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
- positive regulation of cell division
- regulation of cell cycle
- neuron apoptotic process
- negative regulation of release of sequestered calcium ion into cytosol
- positive regulation of protein metabolic process
- positive regulation of smooth muscle cell differentiation
- positive regulation of chemotaxis
- negative regulation of T cell activation
- defense response to fungus
- negative regulation of phagocytosis
- positive regulation of peptidyl-tyrosine phosphorylation
- positive regulation of inflammatory response
- positive regulation of protein secretion
- negative regulation of epithelial cell proliferation
- positive regulation of epithelial cell proliferation
- epithelial cell proliferation
- inner ear development
- positive regulation of smooth muscle cell proliferation
- negative regulation of skeletal muscle tissue development
- digestive tract development
- lymph node development
- positive regulation of isotype switching to IgA isotypes
- lung alveolus development
- positive regulation of fibroblast proliferation
- muscle cell cellular homeostasis
- positive regulation of transcription by RNA polymerase II
- positive regulation of DNA-templated transcription
- negative regulation of DNA-templated transcription
- negative regulation of cell cycle
- positive regulation of epidermal growth factor receptor signaling pathway
- negative regulation of myoblast differentiation
- negative regulation of fat cell differentiation
- negative regulation of cell differentiation
- positive regulation of regulatory T cell differentiation
- regulation of regulatory T cell differentiation
- cell-cell junction organization
- regulatory T cell differentiation
- negative regulation of blood vessel endothelial cell migration
- positive regulation of blood vessel endothelial cell migration
- positive regulation of MAPK cascade
- surfactant homeostasis
- positive regulation of canonical NF-kappaB signal transduction
- positive regulation of vascular permeability
- positive regulation of apoptotic process
- T cell homeostasis
- myelination
- positive regulation of odontogenesis
- odontogenesis of dentin-containing tooth
- positive regulation of protein import into nucleus
- regulation of protein import into nucleus
- negative regulation of T cell proliferation
- regulation of cell population proliferation
- T cell activation
- T cell proliferation
- myofibroblast differentiation
- response to immobilization stress
- positive regulation of protein dephosphorylation
- response to laminar fluid shear stress
- response to vitamin D
- positive regulation of collagen biosynthetic process
- regulation of actin cytoskeleton organization
- mononuclear cell proliferation
- positive regulation of superoxide anion generation
- receptor catabolic process
- positive regulation of tumor necrosis factor production
- positive regulation of interleukin-6 production
- positive regulation of interleukin-17 production
- negative regulation of interleukin-17 production
- regulation of interleukin-23 production
- response to progesterone
- response to estradiol
- positive regulation of exit from mitosis
- positive regulation of protein-containing complex assembly
- membrane protein intracellular domain proteolysis
- animal organ regeneration
- mammary gland development
- positive regulation of cell migration
- regulation of cell migration
- osteoclast differentiation
- negative regulation of cell growth
- negative regulation of ossification
- T cell differentiation
- hyaluronan catabolic process
- negative regulation of cell-cell adhesion
- neural tube development
- regulation of striated muscle tissue development
- response to organic cyclic compound
- positive regulation of microglia differentiation
- oligodendrocyte development
- negative regulation of macrophage cytokine production
- positive regulation of fibroblast migration
- macrophage derived foam cell differentiation
- positive regulation of epithelial to mesenchymal transition
- negative regulation of extracellular matrix disassembly
- negative regulation of gene expression
- positive regulation of gene expression
- positive regulation of vascular endothelial growth factor production
- regulation of gene expression
- gene expression
- response to organic substance
- response to glucose
- response to wounding
- response to xenobiotic stimulus
- germ cell migration
- negative regulation of cell population proliferation
- positive regulation of cell population proliferation
- cell population proliferation
- female pregnancy
- heart development
- endoderm development
- salivary gland morphogenesis
- negative regulation of neuroblast proliferation
- Notch signaling pathway
- transforming growth factor beta receptor signaling pathway
- inflammatory response
- intracellular calcium ion homeostasis
- phosphate-containing compound metabolic process
- ATP biosynthetic process
- protein export from nucleus
- aortic valve morphogenesis
- heart valve morphogenesis
- negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
- tolerance induction to self antigen
- adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
- connective tissue replacement involved in inflammatory response wound healing
- hematopoietic progenitor cell differentiation
- columnar/cuboidal epithelial cell maturation
- chondrocyte differentiation
- sprouting angiogenesis
- regulation of sodium ion transport
- negative regulation of protein phosphorylation
- neural tube closure
- epithelial to mesenchymal transition
- cell activation
- morphogenesis of a branching structure
- response to hypoxia
- ureteric bud development
- vasculogenesis
- cell morphogenesis
- negative regulation of transcription by RNA polymerase II
Protein families (Pfam)
InterPro annotations
CATH domain