PDBe 5vkj

X-ray diffraction
2.12Å resolution

Crystal structure of human CD22 Ig domains 1-3

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
B-cell receptor CD22 Chain: A
Molecule details ›
Chain: A
Length: 324 amino acids
Theoretical weight: 36.66 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: P20273 (Residues: 20-330; Coverage: 38%)
  • Best match: P20273-5 (Residues: 4-158)
Gene names: CD22, SIGLEC2
Sequence domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CLSI BEAMLINE 08ID-1
Spacegroup: C2
Unit cell:
a: 126.807Å b: 56.569Å c: 49.434Å
α: 90° β: 110.7° γ: 90°
R-values:
R R work R free
0.204 0.202 0.232
Expression system: Homo sapiens