› › Structure analysis

Crystal Structure of Human Renin in Complex with a biphenylpipderidinylcarbinol

X-ray diffraction
2.6Å resolution
PDB entry 5v8v coloured by chain, front view.
PDB entry 5v8v coloured by chain, side view.
PDB entry 5v8v coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Renin
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 14276.21 Å2
Buried surface area: 209.9 Å2
Dissociation area: 104.95 Å2
Dissociation energy (ΔGdiss): -6.18 kcal/mol
Dissociation entropy (TΔSdiss): 2.95 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-133565
Assembly 2
Download    3D Visualisation
Assembly Name: Renin
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 14279.99 Å2
Buried surface area: 205.56 Å2
Dissociation area: 102.78 Å2
Dissociation energy (ΔGdiss): -5.18 kcal/mol
Dissociation entropy (TΔSdiss): 2.96 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-133565

Macromolecules

Renin
Chains: A, B
Length: 337 amino acids
Theoretical weight: 36.94 KDa
Source organism: Homo sapiens
Expression system: Baculoviridae
UniProt:
  • Canonical: P00797 (Residues: 70-406; Coverage: 88%)
Gene name: REN
Pfam: Eukaryotic aspartyl protease
InterPro:
CATH: Acid Proteases
Renin in PDB entry 5v8v, assembly 1, front view.
Renin in PDB entry 5v8v, assembly 1, side view.
Renin in PDB entry 5v8v, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links