5v7u

X-ray diffraction
1.64Å resolution

Cyrstal structure of anti-Tau antibody CBTAU-22.1 Fab

Released:
Source organism: Homo sapiens
Entry authors: Zhu X, Zhang H, Wilson IA

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
CBTAU-22.1 Fab light chain Chain: L
Molecule details ›
Chain: L
Length: 219 amino acids
Theoretical weight: 24.09 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
CBTAU-22.1 Fab heavy chain Chain: H
Molecule details ›
Chain: H
Length: 224 amino acids
Theoretical weight: 23.89 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B
Spacegroup: P21
Unit cell:
a: 52.467Å b: 67.229Å c: 62.47Å
α: 90° β: 94.4° γ: 90°
R-values:
R R work R free
0.178 0.176 0.216
Expression system: Homo sapiens