5v2w

X-ray diffraction
2.3Å resolution

Crystal structure of a LuxS from salmonella typhi

Released:
Entry authors: Perumal P, Raina R, Manoj Kumar P, Arockisamy A, SundaraBaalaji N

Function and Biology Details

Reaction catalysed:
S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = L-homocysteine + (4S)-4,5-dihydroxypentan-2,3-dione
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
S-ribosylhomocysteine lyase Chains: A, B
Molecule details ›
Chains: A, B
Length: 179 amino acids
Theoretical weight: 20.44 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhi
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8Z4D7 (Residues: 1-171; Coverage: 100%)
Gene names: STY2943, luxS, t2714
Sequence domains: S-Ribosylhomocysteinase (LuxS)
Structure domains: S-ribosylhomocysteinase (LuxS)

Ligands and Environments

1 bound ligand:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E SUPERBRIGHT
Spacegroup: P21
Unit cell:
a: 48.33Å b: 65.453Å c: 54.242Å
α: 90° β: 106.55° γ: 90°
R-values:
R R work R free
0.192 0.189 0.252
Expression system: Escherichia coli