5uwc

X-ray diffraction
2.4Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Interleukin-3 receptor subunit alpha Chain: G
Molecule details ›
Chain: G
Length: 288 amino acids
Theoretical weight: 33.25 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P26951 (Residues: 20-307; Coverage: 80%)
Gene names: IL3R, IL3RA
Sequence domains:
Structure domains:
Interleukin-3 Chain: I
Molecule details ›
Chain: I
Length: 122 amino acids
Theoretical weight: 13.97 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P08700 (Residues: 31-152; Coverage: 92%)
Gene name: IL3
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, FUL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P61
Unit cell:
a: 106.461Å b: 106.461Å c: 96.116Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.218 0.216 0.242
Expression systems:
  • Spodoptera frugiperda
  • Escherichia coli