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X-ray diffraction
2.1Å resolution

THE STRUCTURE OF THE MAP KINASE P38 AT 2.1 ANGSTROMS RESOLUTION

Released:
Source organism: Mus musculus
Primary publication:
The structure of mitogen-activated protein kinase p38 at 2.1-A resolution.
Proc. Natl. Acad. Sci. U.S.A. 94 2327-32 (1997)
PMID: 9122194

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 14 Chain: A
Molecule details ›
Chain: A
Length: 379 amino acids
Theoretical weight: 43.38 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P47811 (Residues: 1-360; Coverage: 100%)
Gene names: Crk1, Csbp1, Csbp2, Mapk14
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P212121
Unit cell:
a: 45.756Å b: 84.928Å c: 123.911Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.157 0.154 0.214
Expression system: Escherichia coli BL21(DE3)