PDBe 5uke

Solution NMR

NMR structure of monomeric human IRAK-M Death Domain R56D, Y61E mutant


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Interleukin-1 receptor-associated kinase 3 Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q9Y616 (Residues: 1-119; Coverage: 20%)
Gene name: IRAK3
Sequence domains: Death domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: DGSA-distance geometry simulated annealing
Chemical shifts: BMR30237  
Expression system: Escherichia coli