PDBe 5ujj

X-ray diffraction
2.1Å resolution

Crystal structure of human H130R tryptophanyl-tRNA synthetase in complex with TrpAMP

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tryptophan--tRNA ligase, cytoplasmic Chains: A, B
Molecule details ›
Chains: A, B
Length: 484 amino acids
Theoretical weight: 54.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P23381 (Residues: 1-471; Coverage: 100%)
Gene names: IFI53, WARS, WRS
Sequence domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: C2
Unit cell:
a: 136.352Å b: 95.277Å c: 99.623Å
α: 90° β: 130.46° γ: 90°
R-values:
R R work R free
0.216 0.216 0.232
Expression system: Escherichia coli BL21(DE3)