5u77

X-ray diffraction
2.16Å resolution

Crystal structure of ORP8 PH domain

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-189858 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Oxysterol-binding protein-related protein 8 Chain: A
Molecule details ›
Chain: A
Length: 123 amino acids
Theoretical weight: 13.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BZF1 (Residues: 149-265; Coverage: 13%)
Gene names: KIAA1451, ORP8, OSBP10, OSBPL8
Sequence domains: PH domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P6522
Unit cell:
a: 57.079Å b: 57.079Å c: 154.949Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.23 0.227 0.274
Expression system: Escherichia coli BL21(DE3)