› 5u70

Electron Microscopy
3.76Å resolution

Chicken Slo2.2 in an open conformation vitrified in the presence of 300 mM NaCl

Released:
DOI: 10.2210/pdb5u70/pdb
PDB entry 5u70 coloured by chain, front view.
PDB entry 5u70 coloured by chain, side view.
PDB entry 5u70 coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Structural Titration of Slo2.2, a Na+-Dependent K+ Channel.
Hite RK, MacKinnon R
Cell 168 390-399.e11 (2017)
PMID: 28111072
Related structures: EMD-8515

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185841 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel subfamily T member 1 Chain: A
Molecule details ›
Chain: A
Length: 1201 amino acids
Theoretical weight: 137.41 KDa
Source organism: Gallus gallus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8QFV0 (Residues: 1-1201; Coverage: 100%)
Gene names: KCNT1, SLACK
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.76Å
Relevant EMDB volumes: EMD-8515
Expression system: Spodoptera frugiperda

Quick links

Citations

20 review citations

Structural insights into the mechanisms of CNBD channel function.
James et al. (2018)
19 more

11 mentions without citation

Structure Determination by Single-Particle Cryo-Electron Microscopy: Only the Sky (and Intrinsic Disorder) is the Limit.
Nwanochie et al. (2019)
10 more