5u52

X-ray diffraction
1.94Å resolution

2 helix minimized version of the B-domain from Protein A (Z34C0 bound to IgG1 Fc (monoclinic form)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Immunoglobulin heavy constant gamma 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 209 amino acids
Theoretical weight: 23.69 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P01857 (Residues: 119-326; Coverage: 63%)
Gene name: IGHG1
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Mini Z domain Chains: E, Z
Molecule details ›
Chains: E, Z
Length: 34 amino acids
Theoretical weight: 4.19 KDa
Source organism: Staphylococcus aureus
Expression system: synthetic construct

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN, GAL, FUC
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P21
Unit cell:
a: 58.392Å b: 76.39Å c: 66.202Å
α: 90° β: 112.99° γ: 90°
R-values:
R R work R free
0.192 0.19 0.228
Expression systems:
  • Cricetulus griseus
  • synthetic construct