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A. aeolicus BioW with AMP and CoA

Source organism: Aquifex aeolicus
Biochemical function: 6-carboxyhexanoate-CoA ligase activity
Biological process: biotin biosynthetic process
Cellular component: not assigned

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EC 6.2.1.14: 6-carboxyhexanoate--CoA ligase

Reaction catalysed:
ATP + 6-carboxyhexanoate + CoA = AMP + diphosphate + 6-carboxyhexanoyl-CoA
Systematic name:
6-carboxyhexanoate:CoA ligase (AMP-forming)
Alternative Name(s):
  • 6-carboxyhexanoyl-CoA synthetase
  • Pimeloyl-CoA synthetase
  • Pimelyl-CoA synthetase

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF03744
Domain description: 6-carboxyhexanoate--CoA ligase
Occurring in:
  1. 6-carboxyhexanoate--CoA ligase
The deposited structure of PDB entry 5tva contains 2 copies of Pfam domain PF03744 (6-carboxyhexanoate--CoA ligase) in 6-carboxyhexanoate--CoA ligase. Showing 1 copy in chain A.

InterPro InterPro annotation
IPR005499
Domain description: 6-carboxyhexanoate--CoA ligase
Occurring in:
  1. 6-carboxyhexanoate--CoA ligase

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