5to6

X-ray diffraction
2.7Å resolution

Structure of the TPR oligomerization domain

Released:
Source organism: Homo sapiens
Entry authors: Pal K, Bandyopadhyay A, Xu Q, Zhou XE, Melcher K, Xu HE

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoprotein TPR Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 141 amino acids
Theoretical weight: 16.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P12270 (Residues: 2-142; Coverage: 6%)
Gene name: TPR

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-F
Spacegroup: P21
Unit cell:
a: 76.79Å b: 34.86Å c: 113.47Å
α: 90° β: 91.85° γ: 90°
R-values:
R R work R free
0.239 0.237 0.288
Expression system: Escherichia coli BL21(DE3)