5tkv

X-ray diffraction
2.7Å resolution

X-RAY CRYSTAL STRUCTURE OF THE "CLOSED" CONFORMATION OF CTP-INHIBITED E. COLI CYTIDINE TRIPHOSPHATE (CTP) SYNTHETASE

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CTP synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 565 amino acids
Theoretical weight: 62.59 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0A7E5 (Residues: 1-545; Coverage: 100%)
Gene names: JW2751, b2780, pyrG
Sequence domains:
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL1-5
Spacegroup: P21212
Unit cell:
a: 159.159Å b: 110.675Å c: 129.487Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.16 0.157 0.208
Expression system: Escherichia coli BL21(DE3)