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HUMAN BETA CARDIAC HEAVY MEROMYOSIN INTERACTING-HEADS MOTIF OBTAINED BY HOMOLOGY MODELING (USING SWISS-MODEL) OF HUMAN SEQUENCE FROM APHONOPELMA HOMOLOGY MODEL (PDB-3JBH), RIGIDLY FITTED TO HUMAN BETA-CARDIAC NEGATIVELY STAINED THICK FILAMENT 3D-RECONSTRUCTION (EMD-2240)

Source organism: Homo sapiens
Biochemical function: structural constituent of muscle
Biological process: cardiac muscle contraction
Cellular component: sarcomere

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF13499
Domain description: EF-hand domain pair
Occurring in:
  1. Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

PF01576
Domain description: Myosin tail
Occurring in:
  1. Myosin-7
The deposited structure of PDB entry 5tby contains 2 copies of Pfam domain PF01576 (Myosin tail) in Myosin-7. Showing 1 copy in chain A.

PF00063
Domain description: Myosin head (motor domain)
Occurring in:
  1. Myosin-7
The deposited structure of PDB entry 5tby contains 2 copies of Pfam domain PF00063 (Myosin head (motor domain)) in Myosin-7. Showing 1 copy in chain A.

PF02736
Domain description: Myosin N-terminal SH3-like domain
Occurring in:
  1. Myosin-7
The deposited structure of PDB entry 5tby contains 2 copies of Pfam domain PF02736 (Myosin N-terminal SH3-like domain) in Myosin-7. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002048
Domain description: EF-hand domain
Occurring in:
  1. Myosin light chain 3
  2. Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
IPR001609
Domain description: Myosin head, motor domain
Occurring in:
  1. Myosin-7
IPR014751
Domain description: DNA repair protein XRCC4-like, C-terminal
Occurring in:
  1. Myosin-7
IPR011992
Domain description: EF-hand domain pair
Occurring in:
  1. Myosin light chain 3
  2. Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
IPR000048
Domain description: IQ motif, EF-hand binding site
Occurring in:
  1. Myosin-7
IPR004009
Domain description: Myosin, N-terminal, SH3-like
Occurring in:
  1. Myosin-7
IPR018247
Domain description: EF-Hand 1, calcium-binding site
Occurring in:
  1. Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
IPR002928
Domain description: Myosin tail
Occurring in:
  1. Myosin-7
IPR036961
Domain description: Kinesin motor domain superfamily
Occurring in:
  1. Myosin-7
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Myosin-7
IPR008989
Domain description: Myosin S1 fragment, N-terminal
Occurring in:
  1. Myosin-7

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