PDBe 5tby

Electron Microscopy
20Å resolution

HUMAN BETA CARDIAC HEAVY MEROMYOSIN INTERACTING-HEADS MOTIF OBTAINED BY HOMOLOGY MODELING (USING SWISS-MODEL) OF HUMAN SEQUENCE FROM APHONOPELMA HOMOLOGY MODEL (PDB-3JBH), RIGIDLY FITTED TO HUMAN BETA-CARDIAC NEGATIVELY STAINED THICK FILAMENT 3D-RECONSTRUCTION (EMD-2240)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Myosin-7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 1935 amino acids
Theoretical weight: 223.45 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P12883 (Residues: 1-1935; Coverage: 100%)
Gene names: MYH7, MYHCB
Sequence domains:
Myosin light chain 3 Chains: C, D
Molecule details ›
Chains: C, D
Length: 195 amino acids
Theoretical weight: 21.96 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P08590 (Residues: 1-195; Coverage: 100%)
Gene name: MYL3
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform Chains: E, F
Molecule details ›
Chains: E, F
Length: 166 amino acids
Theoretical weight: 18.81 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P10916 (Residues: 1-166; Coverage: 100%)
Gene names: MLC2, MYL2
Sequence domains: EF-hand domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 20Å
Relevant EMDB volumes: EMD-2240