EC 3.6.5.2: Small monomeric GTPase
Reaction catalysed:
GTP + H(2)O = GDP + phosphate
Systematic name:
GTP phosphohydrolase (cell-regulating)
GO terms
Biochemical function:
Biological process:
- sensory perception of light stimulus
- visual perception
- type I pneumocyte differentiation
- epithelial tube branching involved in lung morphogenesis
- positive regulation of glial cell proliferation
- neuron apoptotic process
- striated muscle cell differentiation
- homeostasis of number of cells within a tissue
- regulation of long-term neuronal synaptic plasticity
- negative regulation of neuron apoptotic process
- skeletal muscle cell differentiation
- positive regulation of Rac protein signal transduction
- regulation of synaptic transmission, GABAergic
- negative regulation of epithelial cell differentiation
- actin cytoskeleton organization
- forebrain astrocyte development
- Rac protein signal transduction
- glial cell proliferation
- positive regulation of gene expression
- gene expression
- visual learning
- cell population proliferation
- Ras protein signal transduction
- signal transduction
- positive regulation of protein phosphorylation
- MAPK cascade
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
IPR017287
Domain description:
Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit
Occurring in:
Occurring in:
Structure domains
CATH domains
2.70.50.40
Class:
Mainly Beta
Architecture:
Distorted Sandwich
Topology:
Coagulation Factor XIII; Chain A, domain 1
Homology:
GMP phosphodiesterase, delta subunit
Occurring in:
