5t2q

X-ray diffraction
1.9Å resolution

Unliganded Human HVEM at 1.9A in P 1 21 1

Released:
Source organism: Homo sapiens
Entry authors: Nemcovicova I, Zajonc DM

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-187821 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tumor necrosis factor receptor superfamily member 14 Chains: A, B
Molecule details ›
Chains: A, B
Length: 108 amino acids
Theoretical weight: 11.45 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q92956 (Residues: 39-142; Coverage: 42%)
Gene names: HVEA, HVEM, TNFRSF14, UNQ329/PRO509
Sequence domains: TNFR/NGFR cysteine-rich region
Structure domains: Tumor Necrosis Factor Receptor, subunit A, domain 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P21
Unit cell:
a: 50.19Å b: 47.51Å c: 67.29Å
α: 90° β: 106.69° γ: 90°
R-values:
R R work R free
0.254 0.252 0.288
Expression system: Spodoptera frugiperda