› 5szn

X-ray diffraction
2.94Å resolution

Protocadherin gamma A9 extracellular cadherin domains 1-5

Released:
DOI: 10.2210/pdb5szn/pdb
PDB entry 5szn coloured by chain, front view.
PDB entry 5szn coloured by chain, side view.
PDB entry 5szn coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
γ-Protocadherin structural diversity and functional implications.
Goodman KM, Rubinstein R, Thu CA, Mannepalli S, Bahna F, Ahlsén G, Rittenhouse C, Maniatis T, Honig B, Shapiro L
OpenAccess logo Elife 5 (2016)
PMID: 27782885

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-187600 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Cadherin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 537 amino acids
Theoretical weight: 59.63 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q91XX9 (Residues: 30-558; Coverage: 59%)
Gene name: Pcdhga9
Sequence domains:
Structure domains: Cadherins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
4 bound ligands:
Ligand MAN 3 x MAN
Ligand NAG 1 x NAG
Ligand CA 15 x CA
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: C2
Unit cell:
a: 191.68Å b: 107.61Å c: 49.87Å
α: 90° β: 97.14° γ: 90°
R-values:
R R work R free
0.244 0.241 0.295
Expression system: Homo sapiens

Quick links

Citations

12 review citations

Regulation of neural circuit formation by protocadherins.
Peek et al. (2017)
11 more

4 mentions without citation

γ-Protocadherin structural diversity and functional implications.
Goodman et al. (2016)
3 more