EC 3.6.4.13: RNA helicase
Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (RNA helix unwinding)
Alternative Name(s):
- CSFV NS3 helicase
- DBP2
- DDX17
- DDX25
- DDX3
- DDX3X
- DDX3Y
- DDX4
- DDX5
- DEAD-box RNA helicase
- DEAD-box protein DED1
- DEAH-box RNA helicase
- DEAH-box protein 2
- DED1
- DbpA
- Dex(H/D) RNA helicase
- EIF4A helicase
- EhDEAD1
- EhDEAD1 RNA helicase
- GRTH/DDX25
- KOKV helicase
- Mtr4p
- NPH-II
- Nonstructural protein 3 helicase
- RHA
- RNA helicase A
- RNA helicase DDX3
- RNA helicase Hera
- RNA-dependent ATPase
- TGBp1 NTPase/helicase domain
- VRH1
EC 3.6.4.12: DNA helicase
Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Systematic name:
ATP phosphohydrolase (DNA helix unwinding)
Alternative Name(s):
- 3' to 5' DNA helicase
- 3'-5' DNA helicase
- 3'-5' PfDH
- 5' to 3' DNA helicase
- AvDH1
- BACH1 helicase
- BLM protein
- BRCA1-associated C-terminal helicase
- BcMCM
- CeWRN-1
- DNA helicase 120
- DNA helicase A
- DNA helicase E
- DNA helicase II
- DNA helicase III
- DNA helicase RECQL5'
- DNA helicase VI
- Dbp9p
- DmRECQ5
- DnaB
- DnaB helicase E1
- HHcsA
- HPif1
- Hel E
- Helicase DnaB
- Helicase HDH IV
- Helicase domain of bacteriophage T7 gene 4 protein helicase
- Hmi1p
- MCM helicase
- MCM protein
- MER3 helicase
- MER3 protein
- MPH1
- PDH120
- PIF1
- PcrA
- PcrA helicase
- PfDH A
- Pfh1p
- UvrD
EC 3.4.22.69: SARS coronavirus main proteinase
Reaction catalysed:
TSAVLQ-|-SGFRK-NH(2) and SGVTFQ-|-GKFKK the two peptides corresponding to the two self-cleavage sites of the SARS 3C-like proteinase are the two most reactive peptide substrates. The enzyme exhibits a strong preference for substrates containing Gln at P1 position and Leu at P2 position.
Systematic name:
-
Alternative Name(s):
- 3C-like protease
- 3cLpro
- Coronavirus 3C-like protease
- Mpro
- SARS 3C-like protease
- SARS coronavirus 3CL protease
- SARS coronavirus main peptidase
- SARS coronavirus main protease
- SARS-CoV 3CLpro enzyme
- SARS-CoV Mpro
- SARS-CoV main protease
- Severe acute respiratory syndrome coronavirus main protease
EC 3.4.19.12: Ubiquitinyl hydrolase 1
Reaction catalysed:
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Systematic name:
-
Alternative Name(s):
- Ubiquitin C-terminal hydrolase
- Ubiquitin carboxyl-terminal hydrolase
- Ubiquitin thiolesterase
- Yeast ubiquitin hydrolase
EC 2.7.7.50: mRNA guanylyltransferase
Reaction catalysed:
GTP + a 5'-diphospho-[mRNA] = diphosphate + a 5'-(5'-triphosphoguanosine)-[mRNA]
Systematic name:
GTP:mRNA guanylyltransferase
Alternative Name(s):
- GTP--RNA guanylyltransferase
- Messenger RNA guanylyltransferase
- Protein lambda-2
- mRNA capping enzyme
EC 2.7.7.48: RNA-directed RNA polymerase
Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Systematic name:
Nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
Alternative Name(s):
- 3D polymerase
- PB1 proteins
- PB2 proteins
- Phage f2 replicase
- Polymerase L
- Q-beta replicase
- RDRP
- RNA nucleotidyltransferase (RNA-directed)
- RNA replicase
- RNA synthetase
- RNA transcriptase
- RNA-dependent RNA polymerase
- RNA-dependent RNA replicase
- RNA-dependent ribonucleate nucleotidyltransferase
- Ribonucleic acid replicase
- Ribonucleic acid-dependent ribonucleate nucleotidyltransferase
- Ribonucleic acid-dependent ribonucleic acid polymerase
- Ribonucleic replicase
- Ribonucleic synthetase
- Transcriptase
EC 2.1.1.57: Methyltransferase cap1
Reaction catalysed:
S-adenosyl-L-methionine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleotide)-[mRNA]
Systematic name:
S-adenosyl-L-methionine:5'-(N(7)-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA] 2-O-methyltransferase
Alternative Name(s):
- Cap1-MTase
- MTR1
- Messenger RNA (nucleoside-2'-)-methyltransferase
- Messenger ribonucleate nucleoside 2'-methyltransferase
- S-adenosyl-L-methionine:mRNA (nucleoside-2'-O)-methyltransferase
- mRNA (nucleoside-2'-O)-methyltransferase
EC 2.1.1.56: mRNA (guanine-N(7))-methyltransferase
Reaction catalysed:
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA]
Systematic name:
S-adenosyl-L-methionine:mRNA (guanine-N(7))-methyltransferase
Alternative Name(s):
- Guanine-7-methyltransferase
- Messenger RNA guanine 7-methyltransferase
- Messenger ribonucleate guanine 7-methyltransferase
- S-adenosyl-L-methionine:mRNA (guanine-7-N)-methyltransferase
GO terms
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Protein family (Pfam)![The deposited structure of PDB entry 5sm9 contains 1 copy of Pfam domain PF06471 (Coronavirus guanine-N7 methyltransferase) in Guanine-N7 methyltransferase nsp14. Showing 1 copy in chain A [auth D].](https://www.ebi.ac.uk/pdbe/static/entry/5sm9_1_D_Pfam_PF06471_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>5sm9</span> contains 1 copy of Pfam domain <span class='highlight'>PF06471 (Coronavirus guanine-N7 methyltransferase)</span> in <span class='highlight'>Guanine-N7 methyltransferase nsp14</span>. Showing 1 copy in chain <span class='highlight'>A [auth D]</span>.")
InterPro annotations