X-ray diffraction
1.22Å resolution

PanDDA analysis group deposition -- Crystal Structure of PHIP in complex with NCL-00023827

Source organism: Homo sapiens
Entry authors: Grosjean H, Aimon A, Krojer T, Talon R, Douangamath A, Koekemoer L, Arrowsmith CH, Edwards A, Bountra C, von Delft F, Biggin PC

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
PH-interacting protein Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 17.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: Q8WWQ0 (Residues: 1315-1440; Coverage: 7%)
Gene names: DCAF14, PHIP, WDR11
Sequence domains: Bromodomain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: C2
Unit cell:
a: 81.51Å b: 26.47Å c: 55.72Å
α: 90° β: 99.68° γ: 90°
R R work R free
0.196 0.196 0.21
Expression system: Escherichia coli