5r60

X-ray diffraction
1.79Å resolution

PanDDA analysis group deposition -- Crystal Structure of FIBRINOGEN-LIKE GLOBE DOMAIN OF HUMAN TENASCIN-C in complex with Z19735067

Released:
Source organism: Homo sapiens
Entry authors: Coker JA, Bezerra GA, von Delft F, Arrowsmith CH, Bountra C, Edwards AM, Yue WW, Marsden BD

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tenascin Chain: A
Molecule details ›
Chain: A
Length: 220 amino acids
Theoretical weight: 25.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P24821 (Residues: 1979-2196; Coverage: 10%)
Gene names: HXB, TNC
Sequence domains: Fibrinogen beta and gamma chains, C-terminal globular domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P41212
Unit cell:
a: 77.34Å b: 77.34Å c: 71.62Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.178 0.176 0.221
Expression system: Escherichia coli