5r4o

X-ray diffraction
1.05Å resolution

PanDDA analysis group deposition of ground-state model of BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF

Released:
Source organism: Homo sapiens
Entry authors: Talon R, Krojer T, Fairhead M, Sethi R, Bradley AR, Aimon A, Collins P, Brandao-Neto J, Douangamath A, Wright N, MacLean E, Renjie Z, Dias A, Brennan PE, Bountra C, Arrowsmith CH, Edwards A, von Delft F

Function and Biology Details

Biochemical function:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleosome-remodeling factor subunit BPTF Chain: A
Molecule details ›
Chain: A
Length: 123 amino acids
Theoretical weight: 14.46 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12830 (Residues: 2917-3037; Coverage: 4%)
Gene names: BPTF, FAC1, FALZ
Sequence domains: Bromodomain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: C2
Unit cell:
a: 111.8Å b: 27.37Å c: 38.32Å
α: 90° β: 96.2° γ: 90°
R-values:
R R work R free
0.169 0.169 0.178
Expression system: Escherichia coli