5qxi

X-ray diffraction
1.64Å resolution

PanDDA analysis group deposition -- Crystal Structure of ATAD2 in complex with PC587

Released:
Source organism: Homo sapiens
Entry authors: Snee M, Talon R, Fowley D, Collins P, Nelson A, Arrowsmith CH, Bountra C, Edwards A, Von-Delft F

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATPase family AAA domain-containing protein 2 Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 15.51 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6PL18 (Residues: 981-1108; Coverage: 9%)
Gene names: ATAD2, L16, PRO2000
Sequence domains: Bromodomain

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P6522
Unit cell:
a: 80.177Å b: 80.177Å c: 138.784Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.158 0.157 0.177
Expression system: Escherichia coli