› 5qte

X-ray diffraction
2.07Å resolution

T. brucei FPPS in complex with CID 4563894

Released:
DOI: 10.2210/pdb5qte/pdb
PDB 5qte coloured by chain and viewed from the front.
PDB 5qte coloured by chain and viewed from the side.
PDB 5qte coloured by chain and viewed from the top.
Source organism: Trypanosoma brucei
Entry authors: Muenzker L, Petrick JK, Schleberger C, Cornaciu I, Marquez JA, Jahnke W

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Farnesyl pyrophosphate synthase Chain: A
Molecule details ›
Chain: A
Length: 369 amino acids
Theoretical weight: 42.17 KDa
Source organism: Trypanosoma brucei
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q86C09 (Residues: 1-367; Coverage: 100%)
Sequence domains: Polyprenyl synthetase

Ligands and Environments

4 bound ligands:
Ligand PKD 1 x PKD
Ligand PO4 2 x PO4
Ligand NA 1 x NA
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: P6122
Unit cell:
a: 60.583Å b: 60.583Å c: 341.208Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.255 0.253 0.283
Expression system: Escherichia coli BL21(DE3)

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