5qte

X-ray diffraction
2.07Å resolution

T. brucei FPPS in complex with CID 4563894

Released:
Source organism: Trypanosoma brucei
Entry authors: Muenzker L, Petrick JK, Schleberger C, Cornaciu I, Marquez JA, Jahnke W

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Farnesyl pyrophosphate synthase Chain: A
Molecule details ›
Chain: A
Length: 369 amino acids
Theoretical weight: 42.17 KDa
Source organism: Trypanosoma brucei
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q86C09 (Residues: 1-367; Coverage: 100%)
Sequence domains: Polyprenyl synthetase

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: P6122
Unit cell:
a: 60.583Å b: 60.583Å c: 341.208Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.255 0.253 0.283
Expression system: Escherichia coli BL21(DE3)