5qst

X-ray diffraction
2.58Å resolution

PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z2447286438

Released:
Source organism: Homo sapiens
Entry authors: Newman JA, Katis VL, Gavard AE, von Delft F, Arrowsmith CH, Edwards A, Bountra C, Gileadi O

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cohesin subunit SA-1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 339 amino acids
Theoretical weight: 39.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WVM7 (Residues: 86-420; Coverage: 27%)
Gene names: SA1, SCC3, STAG1
Sequence domains: STAG domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P1
Unit cell:
a: 66.598Å b: 72.046Å c: 118.412Å
α: 94.81° β: 98.61° γ: 115.22°
R-values:
R R work R free
0.232 0.23 0.271
Expression system: Escherichia coli