› 5qsq

X-ray diffraction
2.48Å resolution

PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z396380540

Released:
DOI: 10.2210/pdb5qsq/pdb
PDB 5qsq coloured by chain and viewed from the front.
PDB 5qsq coloured by chain and viewed from the side.
PDB 5qsq coloured by chain and viewed from the top.
Source organism: Homo sapiens
Entry authors: Newman JA, Katis VL, Gavard AE, von Delft F, Arrowsmith CH, Edwards A, Bountra C, Gileadi O

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cohesin subunit SA-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 459 amino acids
Theoretical weight: 52.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WVM7 (Residues: 459-915; Coverage: 36%)
Gene names: SA1, SCC3, STAG1

Ligands and Environments

1 bound ligand:
Ligand HR5 2 x HR5
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P21212
Unit cell:
a: 155.168Å b: 167.216Å c: 47.617Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.225 0.289
Expression system: Escherichia coli

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