5qsq

X-ray diffraction
2.48Å resolution

PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z396380540

Released:
Source organism: Homo sapiens
Entry authors: Newman JA, Katis VL, Gavard AE, von Delft F, Arrowsmith CH, Edwards A, Bountra C, Gileadi O

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cohesin subunit SA-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 459 amino acids
Theoretical weight: 52.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WVM7 (Residues: 459-915; Coverage: 36%)
Gene names: SA1, SCC3, STAG1

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P21212
Unit cell:
a: 155.168Å b: 167.216Å c: 47.617Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.225 0.289
Expression system: Escherichia coli