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PanDDA analysis group deposition -- Crystal Structure of human Brachyury G177D variant in complex with Z54571979

X-ray diffraction
1.87Å resolution
PDB entry 5qsd coloured by chain, front view.
PDB entry 5qsd coloured by chain, side view.
PDB entry 5qsd coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: T-box transcription factor T
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Multimeric state: monomeric
Accessible surface area: 9306.6 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-127349

Macromolecules

T-box transcription factor T
Chain: A
Length: 172 amino acids
Theoretical weight: 19.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O15178 (Residues: 41-211; Coverage: 39%)
Gene names: T, TBXT
Pfam: T-box
InterPro:
T-box transcription factor T in PDB entry 5qsd, assembly 1, front view.
T-box transcription factor T in PDB entry 5qsd, assembly 1, side view.
T-box transcription factor T in PDB entry 5qsd, assembly 1, top view.
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