› 5qqa

X-ray diffraction
2.2Å resolution

PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOOA000648a

Released:
DOI: 10.2210/pdb5qqa/pdb
PDB 5qqa coloured by chain and viewed from the front.
PDB 5qqa coloured by chain and viewed from the side.
PDB 5qqa coloured by chain and viewed from the top.
Source organism: Trypanosoma cruzi
Entry authors: Petrick JK, Nelson ER, Muenzker L, Krojer T, Douangamath A, Brandao-Neto J, von Delft F, Dekker C, Jahnke W

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Farnesyl diphosphate synthase Chain: A
Molecule details ›
Chain: A
Length: 364 amino acids
Theoretical weight: 41.36 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WS26 (Residues: 64-425; Coverage: 85%)
Sequence domains: Polyprenyl synthetase

Ligands and Environments

4 bound ligands:
Ligand SO4 2 x SO4
Ligand ACT 1 x ACT
Ligand ZN 2 x ZN
Ligand LZV 1 x LZV
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P6122
Unit cell:
a: 57.809Å b: 57.809Å c: 396.974Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.207 0.204 0.276
Expression system: Escherichia coli

Quick links