› 5qq7

X-ray diffraction
1.61Å resolution

PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOOA000562a

Released:
DOI: 10.2210/pdb5qq7/pdb
PDB entry 5qq7 coloured by chain, front view.
PDB entry 5qq7 coloured by chain, side view.
PDB entry 5qq7 coloured by chain, top view.
Source organism: Trypanosoma cruzi
Entry authors: Petrick JK, Nelson ER, Muenzker L, Krojer T, Douangamath A, Brandao-Neto J, von Delft F, Dekker C, Jahnke W

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186689 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Farnesyl diphosphate synthase Chain: A
Molecule details ›
Chain: A
Length: 364 amino acids
Theoretical weight: 41.36 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8WS26 (Residues: 64-425; Coverage: 85%)
Sequence domains: Polyprenyl synthetase

Ligands and Environments

4 bound ligands:
Ligand SO4 2 x SO4
Ligand ACT 1 x ACT
Ligand ZN 2 x ZN
Ligand LXM 1 x LXM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P6122
Unit cell:
a: 57.759Å b: 57.759Å c: 396.037Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.194 0.192 0.233
Expression system: Escherichia coli

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