X-ray diffraction
1.6Å resolution

PanDDA analysis group deposition -- Crystal Structure of T. cruzi FPPS in complex with FMOPL000416a

Source organism: Trypanosoma cruzi
Entry authors: Petrick JK, Nelson ER, Muenzker L, Krojer T, Douangamath A, Brandao-Neto J, von Delft F, Dekker C, Jahnke W

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Farnesyl diphosphate synthase Chain: A
Molecule details ›
Chain: A
Length: 364 amino acids
Theoretical weight: 41.36 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli
  • Canonical: Q8WS26 (Residues: 64-425; Coverage: 85%)
Sequence domains: Polyprenyl synthetase

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P6122
Unit cell:
a: 57.831Å b: 57.831Å c: 397.468Å
α: 90° β: 90° γ: 120°
R R work R free
0.198 0.196 0.237
Expression system: Escherichia coli