X-ray diffraction
1.65Å resolution

Crystal structure of human lung surfactant protein D trimeric fragment with bound ligand Salmonella enterica Minnesota R5 oligosaccharide


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Pulmonary surfactant-associated protein D Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 177 amino acids
Theoretical weight: 18.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P35247 (Residues: 201-375; Coverage: 49%)
Gene names: COLEC7, PSPD, SFTP4, SFTPD
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: K5B, GMH, GLC
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P21
Unit cell:
a: 55.679Å b: 108.51Å c: 56.17Å
α: 90° β: 92.89° γ: 90°
R R work R free
0.166 0.165 0.187
Expression system: Escherichia coli BL21(DE3)