X-ray diffraction
3.9Å resolution

CH3 chimera of human 14-3-3 sigma with the StARD1 peptide including Ser57


Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero trimer (preferred)
homo dimer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
14-3-3 protein sigma; Steroidogenic acute regulatory protein, mitochondrial Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 248 amino acids
Theoretical weight: 27.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P31947 (Residues: 1-231; Coverage: 93%)
  • Canonical: P49675 (Residues: 54-62; Coverage: 3%)
Gene names: HME1, SFN, STAR, STARD1
Sequence domains: 14-3-3 protein
Structure domains: 14-3-3 domain
Undetermined peptide Chain: H
Molecule details ›
Chain: H
Length: 4 amino acids
Theoretical weight: 358 Da
Source organism: Homo sapiens
Expression system: Escherichia coli

Ligands and Environments

3 bound ligands:
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P41212
Unit cell:
a: 123.251Å b: 123.251Å c: 162.447Å
α: 90° β: 90° γ: 90°
R R work R free
0.212 0.209 0.248
Expression system: Escherichia coli