Protein Data Bank in Europe

Chain: A
Length: 1970 amino acids
Theoretical weight: 217.44 KDa
Source organism: Bos taurus
UniProt:

• Canonical: G3MZY8 (Residues: 1-1970; Coverage: 100%)

Gene name: POLR2A
Pfam:

• RNA polymerase Rpb1, domain 1
• RNA polymerase Rpb1, domain 2
• RNA polymerase Rpb1, domain 3
• RNA polymerase Rpb1, domain 4
• RNA polymerase Rpb1, domain 5
• RNA polymerase Rpb1, domain 6
• RNA polymerase Rpb1, domain 7
• RNA polymerase Rpb1 C-terminal repeat

InterPro:

• RNA polymerase Rpb1, clamp domain superfamily
• RNA polymerase Rpb1, domain 1
• DNA-directed RNA polymerase, subunit beta-prime
• RNA polymerase, N-terminal
• RNA polymerase, alpha subunit
• RNA polymerase Rpb1, domain 3
• RNA polymerase Rpb1, domain 3 superfamily
• RNA polymerase Rpb1, funnel domain superfamily
• RNA polymerase Rpb1, domain 4
• RNA polymerase Rpb1, domain 5
• RNA polymerase Rpb1, domain 6
• RNA polymerase Rpb1, domain 7
• RNA polymerase Rpb1, domain 7 superfamily
• RNA polymerase II, heptapeptide repeat, eukaryotic

Chain: B
Length: 1174 amino acids
Theoretical weight: 134.04 KDa
Source organism: Bos taurus
UniProt:

• Canonical: A5PJW8 (Residues: 1-1174; Coverage: 100%)

Gene name: POLR2B
Pfam:

• RNA polymerase beta subunit
• RNA polymerase Rpb2, domain 2
• RNA polymerase Rpb2, domain 3
• RNA polymerase Rpb2, domain 4
• RNA polymerase Rpb2, domain 5
• RNA polymerase Rpb2, domain 6
• RNA polymerase Rpb2, domain 7

InterPro:

• DNA-directed RNA polymerase, subunit 2
• RNA polymerase, beta subunit, protrusion
• RNA polymerase Rpb2, domain 2
• RNA polymerase Rpb2, domain 2 superfamily
• RNA polymerase Rpb2, domain 3
• RNA polymerase Rpb2, domain 4
• RNA polymerase Rpb2, domain 5
• DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
• DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily
• RNA polymerase Rpb2, OB-fold
• RNA polymerase, beta subunit, conserved site
• RNA polymerase Rpb2, domain 7

Chain: C
Length: 275 amino acids
Theoretical weight: 31.47 KDa
Source organism: Bos taurus
UniProt:

• Canonical: Q3T0Q3 (Residues: 1-275; Coverage: 100%)

Gene name: POLR2C
Pfam:

• RNA polymerase Rpb3/Rpb11 dimerisation domain
• RNA polymerase Rpb3/RpoA insert domain

InterPro:

• RNA polymerase, RBP11-like subunit
• DNA-directed RNA polymerase subunit Rpo3/Rpb3/RPAC1
• DNA-directed RNA polymerase, RpoA/D/Rpb3-type
• DNA-directed RNA polymerase, 30-40kDa subunit, conserved site
• DNA-directed RNA polymerase, insert domain superfamily
• DNA-directed RNA polymerase, insert domain

CATH:

• RNA polymerase, RBP11-like subunit
• DNA-directed RNA polymerase, insert domain

Chain: D
Length: 142 amino acids
Theoretical weight: 16.35 KDa
Source organism: Bos taurus
UniProt:

• Canonical: Q1JQ91 (Residues: 1-142; Coverage: 100%)

Gene name: POLR2D
Pfam: RNA polymerase Rpb4
InterPro:

• HRDC-like superfamily
• DNA-directed RNA polymerase II subunit Rpb4-like
• Rpb4/RPC9 superfamily
• RNA polymerase Rpb4/RPC9, core
• RNA polymerase subunit Rpb4/RPC9

CATH: Growth Hormone; Chain: A;

Chain: E
Length: 210 amino acids
Theoretical weight: 24.51 KDa
Source organism: Bos taurus
UniProt:

• Canonical: Q2T9T3 (Residues: 1-210; Coverage: 100%)

Gene name: POLR2E
Pfam:

• RNA polymerase Rpb5, N-terminal domain
• RNA polymerase Rpb5, C-terminal domain

InterPro:

• DNA-directed RNA polymerase subunit Rpo5/Rpb5
• RNA polymerase Rpb5, N-terminal domain superfamily
• RNA polymerase, Rpb5, N-terminal
• RPB5-like RNA polymerase subunit superfamily
• RNA polymerase, subunit H/Rpb5 C-terminal
• RNA polymerase, subunit H/Rpb5, conserved site

CATH:

• RNA polymerase, Rpb5, N-terminal domain
• RPB5-like RNA polymerase subunit

Chain: F
Length: 127 amino acids
Theoretical weight: 14.49 KDa
Source organism: Bos taurus
UniProt:

• Canonical: Q32PE0 (Residues: 1-127; Coverage: 100%)

Gene name: POLR2F
Pfam: RNA polymerase Rpb6
InterPro:

• Archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit
• DNA-directed RNA polymerase, subunit RPB6
• RPB6/omega subunit-like superfamily
• RNA polymerase, subunit omega/Rpo6/RPB6
• DNA-directed RNA polymerase, 14-18kDa subunit, conserved site

CATH: Eukaryotic RPB6 RNA polymerase subunit

Chain: G
Length: 172 amino acids
Theoretical weight: 19.31 KDa
Source organism: Bos taurus
UniProt:

• Canonical: Q5E9B8 (Residues: 1-172; Coverage: 100%)

Gene name: POLR2G
Pfam:

• SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
• S1 RNA binding domain

InterPro:

• RNA polymerase Rpb7-like, N-terminal domain superfamily
• RNA polymerase subunit Rpb7-like
• RNA polymerase Rpb7-like , N-terminal
• S1 domain
• Nucleic acid-binding, OB-fold

CATH:

• RNA polymerase Rpb7-like, N-terminal domain
• Nucleic acid-binding proteins

Chain: H
Length: 150 amino acids
Theoretical weight: 17.16 KDa
Source organism: Bos taurus
UniProt:

• Canonical: F2Z4H3 (Residues: 1-150; Coverage: 100%)

Gene name: POLR2H
Pfam: RNA polymerase Rpb8
InterPro:

• Nucleic acid-binding, OB-fold
• DNA-directed RNA polymerases I, II, and III subunit RPABC3

CATH: Nucleic acid-binding proteins

Chain: I
Length: 125 amino acids
Theoretical weight: 14.51 KDa
Source organism: Bos taurus
UniProt:

• Canonical: Q32P73 (Residues: 1-125; Coverage: 100%)

Gene name: POLR2I
Pfam:

• RNA polymerases M/15 Kd subunit
• Transcription factor S-II (TFIIS)

InterPro:

• DNA-directed RNA polymerase subunit/transcription factor S
• DNA-directed RNA polymerase, M/15kDa subunit
• DNA-directed RNA polymerase M, 15kDa subunit, conserved site
• Pol II subunit B9, C-terminal zinc ribbon
• Zinc finger, TFIIS-type

Chain: J
Length: 67 amino acids
Theoretical weight: 7.66 KDa
Source organism: Bos taurus
UniProt:

• Canonical: Q32P78 (Residues: 1-67; Coverage: 100%)

Gene name: POLR2L
Pfam: RNA polymerases N / 8 kDa subunit
InterPro:

• DNA-directed RNA polymerase subunit RPABC5/Rpb10
• RNA polymerase subunit RPB10
• RNA polymerases, subunit N, zinc binding site

CATH: Homeodomain-like

Chain: K
Length: 117 amino acids
Theoretical weight: 13.31 KDa
Source organism: Bos taurus
UniProt:

• Canonical: Q32P79 (Residues: 1-117; Coverage: 100%)

Gene name: POLR2J
Pfam:

• RNA polymerase Rpb3/Rpb11 dimerisation domain
• RNA polymerase Rpb3/Rpb11 dimerisation domain

InterPro:

• RNA polymerase, RBP11-like subunit
• RNA polymerase RBP11
• DNA-directed RNA polymerase subunit Rpo11-like
• DNA-directed RNA polymerase, RBP11-like dimerisation domain
• DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site

CATH: RNA polymerase, RBP11-like subunit

Chain: L
Length: 58 amino acids
Theoretical weight: 7.02 KDa
Source organism: Bos taurus
UniProt:

• Canonical: Q3ZBC0 (Residues: 1-58; Coverage: 100%)

Gene name: POLR2K
Pfam: DNA directed RNA polymerase, 7 kDa subunit
InterPro:

• DNA-directed RNA polymerases I, II, and III subunit RPABC4
• RNA polymerase subunit RPABC4/transcription elongation factor Spt4
• RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4

CATH: RNA polymerase ii, chain L

Chain: Y
Length: 117 amino acids
Theoretical weight: 13.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:

• Canonical: P63272 (Residues: 1-117; Coverage: 100%)

Gene names: SPT4H, SUPT4H, SUPT4H1
Pfam: Spt4/RpoE2 zinc finger
InterPro:

• RNA polymerase subunit RPABC4/transcription elongation factor Spt4
• Transcription initiation Spt4
• Spt4 superfamily
• Spt4/RpoE2 zinc finger

CATH: Herpes Virus-1

Chain: Z
Length: 1087 amino acids
Theoretical weight: 121.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:

• Canonical: O00267 (Residues: 1-1087; Coverage: 100%)

Gene names: SPT5, SPT5H, SUPT5H
Pfam:

• Spt5 transcription elongation factor, acidic N-terminal
• Early transcription elongation factor of RNA pol II, NGN section
• KOW motif

InterPro:

• Transcription elongation factor Spt5, eukaryote
• Transcription elongation factor SPT5
• Spt5 transcription elongation factor, N-terminal
• NusG, N-terminal domain superfamily
• NusG-like, N-terminal
• NGN domain
• NGN domain, eukaryotic
• KOW
• Spt5, KOW domain repeat 1
• Large ribosomal subunit protein uL2, domain 2
• Spt5, KOW domain repeat 2
• Translation protein SH3-like domain superfamily
• Spt5, KOW domain repeat 3
• Spt5, KOW domain repeat 4
• Spt5, KOW domain repeat 5
• Spt5 C-terminal domain
• Spt5, KOW domain repeat 6