Function and Biology

Globin sensor domain of AfGcHK (FeIII form) in complex with cyanide

Source organism: Anaeromyxobacter sp. Fw109-5
Biochemical function: heme binding
Biological process: not assigned
Cellular component: not assigned

EC 2.7.13.3: Histidine kinase

Reaction catalysed:
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Systematic name:
ATP:protein-L-histidine N-phosphotransferase
Alternative Name(s):
  • EnvZ
  • HK1
  • HP165
  • Histidine protein kinase
  • Protein histidine kinase
  • Protein kinase
  • Protein kinase (histidine)
  • Sln1p

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF11563
Domain description: Protoglobin
Occurring in:
  1. Globin-coupled histidine kinase
The deposited structure of PDB entry 5ohe contains 8 copies of Pfam domain PF11563 (Protoglobin) in Globin-coupled histidine kinase. Showing 1 copy in chain F.

InterPro InterPro annotations
IPR039379
Domain description: Protoglobin, globin sensor domain
Occurring in:
  1. Globin-coupled histidine kinase
IPR044398
Domain description: Globin-sensor domain
Occurring in:
  1. Globin-coupled histidine kinase
IPR009050
Domain description: Globin-like superfamily
Occurring in:
  1. Globin-coupled histidine kinase
IPR012292
Domain description: Globin/Protoglobin
Occurring in:
  1. Globin-coupled histidine kinase