X-ray diffraction
2.7Å resolution

Crystal structure of thermostabilised human C5a anaphylatoxin chemotactic receptor 1 (C5aR) in complex with NDT9513727


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
C5a anaphylatoxin chemotactic receptor 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 317 amino acids
Theoretical weight: 35.74 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
  • Canonical: P21730 (Residues: 31-333; Coverage: 87%)
Gene names: C5AR, C5AR1, C5R1
Sequence domains: 7 transmembrane receptor (rhodopsin family)

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P21
Unit cell:
a: 83.093Å b: 51.096Å c: 118.936Å
α: 90° β: 106.73° γ: 90°
R R work R free
0.21 0.208 0.238
Expression system: Spodoptera frugiperda