5o7y

X-ray diffraction
1.97Å resolution

Thebaine 6-O-demethylase (T6ODM) from Papaver somniferum in complex with succinate

Released:

Function and Biology Details

Reaction catalysed:
Thebaine + 2-oxoglutarate + O(2) = neopinone + formaldehyde + succinate + CO(2)
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thebaine 6-O-demethylase Chain: A
Molecule details ›
Chain: A
Length: 367 amino acids
Theoretical weight: 40.94 KDa
Source organism: Papaver somniferum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D4N500 (Residues: 1-364; Coverage: 100%)
Gene names: DIOX1, T6ODM
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: Agilent SuperNova
Spacegroup: P212121
Unit cell:
a: 47.231Å b: 87.028Å c: 94.171Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.165 0.163 0.207
Expression system: Escherichia coli BL21(DE3)