› › Structure analysis

p53 cancer mutant Y220C in complex with compound MB240

X-ray diffraction
1.44Å resolution
PDB entry 5o1a coloured by chain, front view.
PDB entry 5o1a coloured by chain, side view.
PDB entry 5o1a coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1
Download    3D Visualisation
Assembly Name: Cellular tumor antigen p53
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 9945.79 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-138105
Assembly 2 (preferred)
Download    3D Visualisation
Assembly Name: Cellular tumor antigen p53
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 9740.1 Å2
Buried surface area: 247.19 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-138105

Macromolecules

Cellular tumor antigen p53
Chains: A, B
Length: 219 amino acids
Theoretical weight: 24.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04637 (Residues: 94-312; Coverage: 56%)
Gene names: P53, TP53
Pfam: P53 DNA-binding domain
InterPro:
CATH: Immunoglobulin-like
Cellular tumor antigen p53 in PDB entry 5o1a, assembly 2, front view.
Cellular tumor antigen p53 in PDB entry 5o1a, assembly 2, side view.
Cellular tumor antigen p53 in PDB entry 5o1a, assembly 2, top view.
Molecule details ›

Search similar proteins

Quick links