› 5o0m

X-ray diffraction
1.9Å resolution

Deglycosylated Nogo Receptor with native disulfide structure 3

Released:
DOI: 10.2210/pdb5o0m/pdb
PDB 5o0m coloured by chain and viewed from the front.
PDB 5o0m coloured by chain and viewed from the side.
PDB 5o0m coloured by chain and viewed from the top.
Source organism: Mus musculus
Primary publication:
Nogo Receptor crystal structures with a native disulfide pattern suggest a novel mode of self-interaction.
Pronker MF, Tas RP, Vlieg HC, Janssen BJC
Acta Crystallogr D Struct Biol 73 860-876 (2017)
PMID: 29095159

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Reticulon-4 receptor Chains: A, B
Molecule details ›
Chains: A, B
Length: 323 amino acids
Theoretical weight: 36.01 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q99PI8 (Residues: 26-337; Coverage: 70%)
Gene names: Ngr1, Nogor, Rtn4r
Sequence domains: Leucine rich repeat
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

1 bound ligand:
Ligand NAG 5 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X6A
Spacegroup: P212121
Unit cell:
a: 46.61Å b: 112.07Å c: 115.13Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.179 0.222
Expression system: Homo sapiens

Quick links

Citations

1 citations in other articles

The Murine Neuronal Receptor NgR1 Is Dispensable for Reovirus Pathogenesis.
Aravamudhan et al. (2022)