5nv9

X-ray diffraction
1.95Å resolution

Substrate-bound outward-open state of a Na+-coupled sialic acid symporter reveals a novel Na+-site

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Putative sodium:solute symporter Chain: A
Molecule details ›
Chain: A
Length: 496 amino acids
Theoretical weight: 54.93 KDa
Source organism: Proteus mirabilis HI4320
Expression system: Escherichia coli
UniProt:
  • Canonical: B4EZY7 (Residues: 1-496; Coverage: 100%)
Gene name: PMI2976
Sequence domains: Sodium:solute symporter family

Ligands and Environments

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: C2
Unit cell:
a: 130.59Å b: 98.07Å c: 54.78Å
α: 90° β: 92.15° γ: 90°
R-values:
R R work R free
0.201 0.199 0.243
Expression system: Escherichia coli