5nst

X-ray diffraction
2.52Å resolution

Human monoclonal antibody with a LAIR1 insertion

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Light Chain of antibody MGD21 Chains: A, C
Molecule details ›
Chains: A, C
Length: 214 amino acids
Theoretical weight: 23.47 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
Heavy Chain of antibody MGD21 Chains: B, D
Molecule details ›
Chains: B, D
Length: 360 amino acids
Theoretical weight: 39.32 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: C2
Unit cell:
a: 169.823Å b: 86.462Å c: 103.998Å
α: 90° β: 126.65° γ: 90°
R-values:
R R work R free
0.221 0.219 0.267
Expression system: Homo sapiens