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Structure of Naa15/Naa10 bound to HypK-THB

Source organisms:
Biochemical function: acyltransferase activity, transferring groups other than amino-acyl groups
Biological process: N-terminal protein amino acid acetylation
Cellular component: NatA complex

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF19026
Domain description: HYPK UBA domain
Occurring in:
  1. Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein
The deposited structure of PDB entry 5nnp contains 2 copies of Pfam domain PF19026 (HYPK UBA domain) in Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein. Showing 1 copy in chain C.

PF00583
Domain description: Acetyltransferase (GNAT) family
Occurring in:
  1. N-acetyltransferase domain-containing protein
The deposited structure of PDB entry 5nnp contains 2 copies of Pfam domain PF00583 (Acetyltransferase (GNAT) family) in N-acetyltransferase domain-containing protein. Showing 1 copy in chain B.

PF12569
Domain description: N-terminal acetyltransferase A, auxiliary subunit
Occurring in:
  1. N-terminal acetyltransferase-like protein
The deposited structure of PDB entry 5nnp contains 2 copies of Pfam domain PF12569 (N-terminal acetyltransferase A, auxiliary subunit) in N-terminal acetyltransferase-like protein. Showing 1 copy in chain A.

PF13181
Domain description: Tetratricopeptide repeat
Occurring in:
  1. N-terminal acetyltransferase-like protein

InterPro InterPro annotations
IPR019734
Domain description: Tetratricopeptide repeat
Occurring in:
  1. N-terminal acetyltransferase-like protein
IPR000182
Domain description: GNAT domain
Occurring in:
  1. N-acetyltransferase domain-containing protein
IPR011990
Domain description: Tetratricopeptide-like helical domain superfamily
Occurring in:
  1. N-terminal acetyltransferase-like protein
IPR021183
Domain description: N-terminal acetyltransferase A, auxiliary subunit
Occurring in:
  1. N-terminal acetyltransferase-like protein
IPR044034
Domain description: Nascent polypeptide-associated complex subunit alpha-like, UBA domain
Occurring in:
  1. Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein
IPR038922
Domain description: Huntingtin-interacting protein K, UBA-like domain
Occurring in:
  1. Nascent polypeptide-associated complex subunit alpha-like UBA domain-containing protein
IPR045047
Domain description: N-acetyltransferase Ard1-like
Occurring in:
  1. N-acetyltransferase domain-containing protein
IPR016181
Domain description: Acyl-CoA N-acyltransferase
Occurring in:
  1. N-acetyltransferase domain-containing protein

Structure domains

CATH CATH domains
3.40.630.30
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Aminopeptidase
Homology: Aminopeptidase
Occurring in:
  1. N-acetyltransferase domain-containing protein
The deposited structure of PDB entry 5nnp contains 2 copies of CATH domain 3.40.630.30 (Aminopeptidase) in N-acetyltransferase domain-containing protein. Showing 1 copy in chain B.
1.25.40.1040
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Occurring in:
  1. N-terminal acetyltransferase-like protein
The deposited structure of PDB entry 5nnp contains 2 copies of CATH domain 1.25.40.1040 (Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat) in N-terminal acetyltransferase-like protein. Showing 1 copy in chain A.

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