EC 3.6.1.56: 2-hydroxy-dATP diphosphatase
Reaction catalysed:
2-hydroxy-dATP + H(2)O = 2-hydroxy-dAMP + diphosphate
Systematic name:
2-hydroxy-dATP diphosphohydrolase
Alternative Name(s):
- (2'-deoxy) ribonucleoside 5'-triphosphate pyrophosphohydrolase
- MTH1
- MTH2
- NUDT1
- Oxidized purine nucleoside triphosphatase
GO terms
Biochemical function:
- 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity
- O6-methyl-dGTP hydrolase activity
- N6-methyl-(d)ATP hydrolase activity
- 2-hydroxy-dATP hydrolase activity
- 2-hydroxy-ATP hydrolase activity
- ATP diphosphatase activity
- metal ion binding
- 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
- snoRNA binding
- hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
- hydrolase activity
- dATP diphosphatase activity
- 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
- protein binding
- RNA binding
Protein family (Pfam)
InterPro annotations
CATH domain