5nfb

X-ray diffraction
1.59Å resolution

Structure of Galectin-3 CRD in complex with compound 4

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-3 Chain: A
Molecule details ›
Chain: A
Length: 176 amino acids
Theoretical weight: 19.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P17931 (Residues: 106-250; Coverage: 58%)
Gene names: LGALS3, MAC2
Sequence domains: Galactoside-binding lectin
Structure domains: Jelly Rolls

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SOLEIL BEAMLINE PROXIMA 1
Spacegroup: P212121
Unit cell:
a: 36.24Å b: 57.95Å c: 62.58Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.16 0.159 0.18
Expression system: Escherichia coli