Electron Microscopy
6.1Å resolution

Microtubule-bound MKLP2 motor domain in the with no nucleotide


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Kinesin-like protein KIF20A Chain: C
Molecule details ›
Chain: C
Length: 501 amino acids
Theoretical weight: 56.02 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: P97329 (Residues: 21-521; Coverage: 57%)
Gene names: Kif20a, Rab6kifl
Sequence domains: Kinesin motor domain
Tubulin alpha-1B chain Chain: A
Molecule details ›
Chain: A
Length: 451 amino acids
Theoretical weight: 50.11 KDa
Source organism: Bos taurus
  • Canonical: P81947 (Residues: 1-451; Coverage: 100%)
Sequence domains:
Tubulin beta-2B chain Chain: B
Molecule details ›
Chain: B
Length: 445 amino acids
Theoretical weight: 49.91 KDa
Source organism: Bos taurus
  • Canonical: Q6B856 (Residues: 1-445; Coverage: 100%)
Gene name: TUBB2B
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 6.1Å
Relevant EMDB volumes: EMD-3621
Expression system: Escherichia coli